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Mass Spectrometry (MS)-based Tech

Database Assisted Shotgun Sequencing (DASS) represents a pioneering advancement grounded in mass spectrometry (MS) for the intricate task of protein sequencing and comprehensive analysis.


Description

Database Assisted Shotgun Sequencing (DASS) represents a pioneering advancement grounded in mass spectrometry (MS) for the intricate task of protein sequencing and comprehensive analysis. Operating at the forefront of technological sophistication, this methodology harnesses the potential of a mass spectrometer to extract intricate mass spectral information from protein specimens. Thereafter, through the intricate orchestration of cutting-edge data processing algorithms in-house, accentuated by purpose-built MS software, this extracted mass spectral data metamorphoses into a rich tapestry of amino acid sequence information, meticulously elucidating the protein's structural essence.

https://www.creative-biolabs.com/preciabseq/other-ms-based-services.htm

Researcher background
DASS achieves full sequence coverage of antibodies, ensuring accurate determination of all amino acid positions, especially in the variable regions of antibodies. Each position in these regions is covered at least 4 times, enhancing the precision of sequencing results.

Are you seeking volunteer growers or other types of volunteers?
No, do not require volunteers.
Is this a multi-year project?
Maybe
Anything else?
DASS utilizes MS to obtain high-resolution peptide information, accurately analyzing various features of antibodies, and overcoming resolution limitations of traditional sequencing methods.

DASS, in conjunction with MS data, can precisely identify key information such as mutations, post-translational modifications, glycosylation, etc., contributing to a deeper understanding of antibody structure and function.

DASS can differentiate between amino acids with similar molecular weights, overcoming the limitations of traditional techniques in identifying indistinguishable amino acids.

DASS is suitable for antibodies from diverse species sources including mouse, rat, chicken, rabbit, sheep, etc. It's also applicable to sequencing various antibody subtypes and forms such as IgM, fluorescent-conjugated antibodies, immobilized antibodies, and more.

DASS employs advanced data processing algorithms and collaborates with MS software to achieve accurate identification and interpretation of antibody sequences.

https://www.creative-biolabs.com/preciabseq/other-ms-based-services.htm
Researcher Location

11788
United States

Disease/Pest Management